Mechanism of action of sedating antihistamines Sex chat profiles online game

Addiction, the biggest problem, can usually be avoided by keeping the dose to 0.5 mg BID or less. Fall risk is increased in the elderly by roughly the same proportions.

Other problems include higher incidence of car accidents (risk x1.5), and hip fractures (risk x 1.8) (Ray, Griffin et al. Similarly, low doses of diazepam (Valium) (2 mg) can be quite effective for dizziness.

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The author prefers to avoid use of alprazolam (Xanax) for vestibular suppression, because of the potential for a difficult withdrawal syndrome.

Anticholinergics also affect compensation, producing a reversible overcompensation if administered after compensation has been attained to a vestibular imbalance (Zee, 1988).

These drugs are often available OTC, or "over the counter". The antihistamine component has side effects of sleepiness and long term weight gain (see below).

Serafin and others (1993) reported that histamine increases firing in MVN cells, mediated through the H2 receptor.

H1 receptors are present in guinea pig vestibular nucleus, but they don't seem to be relevant to vertigo, and it does not appear that the therapeutic effects of H1 receptor blockers can be attributed to blockate of H1 (Timmerman, 1994).

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